All of the dates are doubleheaders unless indicated by an asterisk (*).
| Date | Opponent | Location | Time/Result |
|---|---|---|---|
| Sat, 19 Feb 2022 |  North Arkansas College | Harrison, AR | 6-4 W, 14-3 W |
| Sun, 20 Feb 2022 | North Arkansas College | Harrison, AR | 12- 2 L, 8-7 L |
| Tue, 22 Feb 2022 |  Three Rivers Community College | Union, MO | Cancelled |
| Sat, 26 Feb 2022 |  St. Louis Community College | Kirkwood, MO | Cancelled |
| Sun, 27 Feb 2022 | St. Louis Community College | Union, MO | Cancelled |
| Wed, 02 Mar 2022 |  State Fair Community College | Sedalia, MO | 10-0 L , 6-5 L |
| Fri, 04 Mar 2022 |  Milwaukee Tech | Union, MO | 5-4 L, 8-3 L |
| Sat, 05 Mar 2022 | Milwaukee Tech | Union, MO | 14-8 W, 4-2 W |
| Tue, 08 Mar 2022 | St. Louis Community College | Kirkwood, MO | Postponed |
| Thr, 10 Mar 2022 |  Lansing | Union, MO | 4- 2 L, 9-1 L |
| Tue, 15 Mar 2022 | Three Rivers Community College | Poplar Bluff, MO | 9-2 L, 7-3 L |
| Mon, 21 Mar 2022 |  Frontier Community College | Fairfield, IL | 2-1 W, 11-1 L |
| Fri, 25 Mar 2022 |  Hesston | Union, MO | 13-12 W, 23-10 L |
| Sat, 26 Mar 2022 | Hesston | Union, MO | 9-6 W, 14-4 W |
| Sun, 27 Mar 2022 |  Jefferson College | Union, MO | 13-5 L, 8-7 L |
| Wed, 30 Mar 2022 |  Lewis & Clark Community College | Godfrey, IL | Cancelled |
| Sat, 02 Apr 2022 | North Arkansas College | Union, MO | 3-1 W, 11-5 L |
| Sun, 03 Apr 2022 | North Arkansas College | Union, MO | 5-4 W, 13-6 L |
| Tue, 05 Apr 2022 |  Spoon River | Union, MO | Cancelled |
| Wed, 06 Apr 2022 | Spoon River | Union, MO | 14-3 W, 12-11 W |
| Sat, 09 Apr 2022 |  North Central | Trenton, MO | 4-0 W, 9-8L |
| Sun, 10 Apr 2022 | North Central | Trenton, MO | 14-1 W, 11-1 W |
| Wed, 13 Apr 2022 | Lewis & Clark Community College | Union, MO | Cancelled |
| Fri, 15 Apr 2022 | North Central | Union, MO | 11- 5 W, 12-5 W |
| Sat, 16 Apr 2022 | North Central | Union, MO | 4-2 L |
| Tue, 19 Apr 2022 |  St. Charles Community College | Cottleville, MO | 12-1 L, 11-1 L |
| Fri, 22 Apr 2022 | Hesston | Hesston, KS | 20 -3 L |
| Sat, 23 Apr 2022 | Hesston | Hesston, KS | 4-2 L, 8-5 W |
| Tue, 26 Apr 2022 |  Mineral Area College | Union, MO | Postponed |
| Wed, 27 Apr 2022 | Lewis & Clark Community College | Godfrey, IL | Cancelled |
| Fri, 29 Apr 2022 | Mineral Area College | Union, MO | Postponed |
| Sat, 30 Apr 2022 | St. Louis Community College | Kirkwood, MO | Cancelled |
| Sun, 01 May 2022 | Mineral Area College | Union, MO | 15-4 L, 12-6 L |
| Mon, 02 May 2022 | Frontier Community College | Union, MO | Cancelled |
| Sat, 07 May 2022 | North Central | Trenton, MO | 11-1 W |
| Sat, 07 May 2022 | North Central | Trenton, MO | 5-3 W |
| Thr, 12 May 2022 |  Northern Oklahoma- Enid | Enid, OK | 9 - 1 L |
| Fri, 13 May 2022 |  Western Oklahoma | Enid, OK | 6 - 5 W |
| Sat, 14 May 2022 |  UA Rich Mountain | Enid, OK | 9 - 0 L |
| Sun, 15 May 2022 |  NJCAA Districts | Enid, OK | TBA |