| Date | Opponent | Location | Time/Result |
|---|
| Fri, 22 Jan 2021 |  Missouri Baptist University- JV | Union, MO | 3:00 PM |
| Fri, 22 Jan 2021 |  John A. Logan College | Union, MO | 7:00 PM |
| Sat, 23 Jan 2021 |  Northeastern Oklahoma A& M | Union, MO | 9:00 AM |
| Sat, 23 Jan 2021 |  John Wood Community College | Union, MO | 1:00 PM |
| Wed, 27 Jan 2021 |  Lewis & Clark Community College | Godfrey, IL | 6:00 AM |
| Sat, 06 Feb 2021 |  Frontier Community College | Union, MO | 12:00 PM |
| Wed, 10 Feb 2021 |  St. Louis Community College | Union, MO | 6:30 PM |
| Fri, 12 Feb 2021 |  Missouri State University- West Plains | Union, MO | 6:30 PM |
| Sat, 13 Feb 2021 |  Rend Lake College | Union, MO | 9:00 AM |
| Sat, 13 Feb 2021 |  Morton College | Union, MO | 1:00 PM |
| Tue, 16 Feb 2021 |  Mineral Area College | Park Hills, MO | 6:30 PM |
| Sat, 20 Feb 2021 |  Spoon River | Canton, IL | TBA |
| Sat, 27 Feb 2021 |  Metropolitan Community College Kansas City | Union, MO | 12:00 PM |
| Wed, 03 Mar 2021 |  Jefferson College | Union, MO | 6:30 PM |
| Sat, 06 Mar 2021 | Metropolitan Community College Kansas City | Kansas City, MO | 12:00 PM |
| Fri, 12 Mar 2021 | St. Louis Community College | Kirkwood, MO | 6:30 PM |
| Wed, 17 Mar 2021 | John Wood Community College | Quincy, IL | 6:30 PM |
| Sat, 20 Mar 2021 |  Lincoln Land Community College | Springfield, IL | 3:30 PM |
| Sat, 20 Mar 2021 |  Southwestern Illinois College | Springfield, IL | 6:00 PM |
| Sun, 21 Mar 2021 |  Parkland College | Champaign, IL | TBA |
| Sun, 21 Mar 2021 |  Illinois Valley Community College | Champaign, IL | TBA |
| Wed, 24 Mar 2021 | Frontier Community College | Fairfield, IL | 6:00 PM |
| Fri, 26 Mar 2021 |  Region 16 Semifinal | Kansas City, MO | 6:00 PM |
| Sat, 27 Mar 2021 | Region 16 Final | Kansas City, MO | 11:00 AM |
